Research

Research

Research

With significant and ongoing technical assistance from our partner, The Institute of Tropical Medicine in Antwerp, SHCH has emerged to be one of the foremost research centers in the country. Other donors are supporting early efforts in Non-Communicable Diseases.

As of August 2015, SHCH is supporting these research studies:

  • Risk factors for acquisition of Salmonella Paratyphi A, Phnom Penh, Cambodia: a qualitative exploration
  • Laboratory evaluation of immunochromatographic antigen tests for the rapid detection of Salmonella Typhi and Salmonella Paratyphi in blood culture supernatants.
  • Surveillance of antimicrobial resistance among consecutive blood culture isolates in tropical settings.
  • Hepatitis C treatment for HIV patients in resource-poor countries: is a public health approach possible?
  • A Screen and Treat Comparison Study: Prevention of cervical cancer in HIV-positive and HIV- women in Cambodia
  • Syndromic approach to neglected infectious diseases (NID) at primary health care level: an international collaboration on integrated diagnosis-treatment platforms

SHCH and ITM researchers have collaborated on a significant number of research findings and have been published in the following articles and poster presentations.

  1. ART and Kidney Function, A Study on the Effect of Renal Failure on the Occurrence of Side Effects in Patients on HAART (Study in collaboration with ITM Antwerp, Belgium; financed by EuropeAid; 2007-2008)
  2. Surveillance of Antimicrobial Resistance Among Consecutive Blood Culture Isolates In Tropical Settings (Study in collaboration with ITM Antwerp, Belgium; 2008-Current)
  3. Comparing Visual Inspection With Acetic Acid to Cytology in Detection of Precancerous Lesions of the Cervix in HIV-Infected Cambodian Women Lim Kruy, SHCH Medical Director, conducted a study on an alternate way of detecting and diagnosing cervival cancer in HIV-infected women using vinegar
  4. Skin and soft tissue infections in Cambodian adults: key bacterial pathogens and resistance patterns. T Phe, E Vlieghe, C Veng, J van Griensven, C Kham, S Thai, B De Smet, J Jacobs
  5. Five-year experience of diagnosis and treatment of melioidosis in Cambodian adult patients Thong Phe, Erika Vlieghe, Chhunheng Veng, Kruy Lim, Chun Kham, Birgit De Smet, Sovann Ieng, J Jacobs
  6. Increase in Salmonella enterica serovar Paratyphi A infections in Phnom Penh, Cambodia, January 2011 to August 2013 E Vlieghe, T Phe, B De Smet, C H Veng, C Kham, D Sar, J van Griensven, K Lim, S Thai, J Jacobs
  7. An Algorithm for Tuberculosis Screening and Diagnosis in People with HIV Dr. Sopheak Thai, Head of Infectious Disease Department at SHCH, contributed to a study published in The New England Journal of Medicine                                
  8. AstraZeneca/AmeriCares Observational Study on Breast Cancer. (2008-Current)
  9. Baseline Antibiotic Consumption and Pattern of Antibiotic Resistance in a Cambodian Referral Hospital
  10. (The Sihanouk Hospital Center of HOPE), Phnom Penh, Cambodia (Study in collaboration with ITM Antwerp, Belgium; 2008-Current)
  11. Impact of Prolonged Detectable HIV Viral Load of the First Line Failure in RSL: Accumulation of Resistance Mutations, Clinical and Immunological Progression (Study in collaboration with ITM Antwerp, Belgium; 2008-Current)
  12. Operational Study on the Implementation of an Algorithm as Proposed in the 2006 WHO Guidelines to Improve the Diagnosis of Tuberculosis Among Adults in HIV-Prevalent and Resource Constrained Settings
  13. For Ambulatory Patients Without Danger Signs (Study in collaboration with the National Center for TB and Leprosy Control and ITM Antwerp, Belgium; financed by WHO - Geneva; 2008-Current)
  14. Study on the Validity of the WHO Definitions of Treatment Failure With the Development of a Scoring System to Predict Virological Failure (Study in collaboration with ITM Antwerp, Belgium; financed by EuropeAid; 2007-2008)
  15. Use of Simplified Medication Adherence Questionnaire (SMAQ) and Visual Analogue Scale (VAS) As Predictive Tools of Virological Failure in a Resource Poor Setting (Study in collaboration with ITM Antwerp, Belgium; financed by EuropeAid; 2007-2008)